Monday, August 3, 2015

Acute Pain in Female Patient

Acute  Pain  in  a  Female  Patient

INTRODUCTION 

    
Large number of patients with abdominal and pelvic pain are reffered to both the gynecologists and surgeons .  The vast majority of cases will be found to have no organic basic and will be categorized as irritable bowel syndrome,  spastic  colon,  pelvic  inflammatory disease or even  "psychosomatic".
 

  The current view is that pains are pains are real and that doctors should not adopt  a dismissive attitude. Several factors including infections , endocrine disorders,pregnancy,childbirth,previous surgery could all be implicated. In addition there could be a psychological overlay with stress and social problems.

  In the chapter we hope to address the differential diagnosis, discuss the recent investigative modalities and the most appropriate treatment for acute pain from reproductive and intestinal tract.

Most causes of pain fit into three categories :
1 .  Causes that originate  in the reproductive tract.
 2.  Causes that originate in the intestinal tract.
3.  Causes that originate in the urinary tract.

THE  ORIGINS   OF  PELVIC  PAIN
  THe  rectum,  lower  colon , cecum, appendix,  terminal  ileum , bladder  and  gynecological organs  are so closely  related and the localization of visual pain so poor that it is not  surprising that pelvic pain could be seen by a variety of specialists . Pain from these areas is largely perceived via the sympathetic nervous  system and there is shared innervations of the vagina cervix inner third of fallopian tubes broad ligament , upper bladder , terminal ileum and large bowel. The  pain travels via the hypogastric  plexus and hypogastric  nerve to the lower thoracic  and lumbar sympathetic chain . The  afferents  enter the cord  between T10 -L1. Pain  from the colon also travels via the parasympathetics to the pelvic plexus , pelvic nerves and enters the cord at S 2-4. The outer third of the fallopian  tube and urethra  are innervated  differently and the afferents enter the cord between T 9 and T10. The  lower vagina , lower bladder and rectosigmoid  junction are innervated  by sacral afferents. The localization of pain is dependent upon convergence of visual and somatic nerves within the central nervous  system in the anterior  horn .  Referred  pain is thought to be due  to the shared  connections of the afferent nervous system  in the posterior root ganglia. Reffered patterns may lead to quite unusual  and  unexpected  sites of pain.


ECTOPIC GESTATION

·         It  is necessary  to exclude an ectopic  pregnancy  in all women of reproductive age group married or otherwise.  The patient's last menstrual  period  and sexual activity pattern are useful but do not eliminate the need to do a pregnancy test. A simple urine pregnancy  test will detect BhCG of even  20 mIU/ml. If inconclusive a serum BhCG should be done . In subacute presentations when diagnosis is not obvious non- invasive  tests namely high resolution transvaginal  scan and serial BhCG estimations  are useful. Normally developing intrauterine pregnancies will have a characterstic doubling rate of BhCG of 1.98 days . When the BhCG does not double it is suggestive of a falling intrauterine pregnancy or an ectopic gestation. If subsequent BhCG values show a declining  trend,one can wait without surgery or medical treatment. Often several  BhCG  estimations and ultrasound have to be performed before a definitive diagnosis is made . Laparoscopy which used to be the gold standard for diagnosis is made.  Laparoscopy  which used to be the gold standard for diagnosis is seldom needed to diagnose  an ectopic gestation . Generally , one  should  be able to see a  gestational sac with a quant of  1000 miu/ mi. Identifying an intrauterine sac does not exclude a co-existing ectopic pregnancy , defined as  heterotopic pregnancy . This is rare , 1 in 5000 pregnancy but is increasing  with more women undergoing treatment with artifical  reproductive techniques (ART) and  pelvic  inflammatory  disease(PID) .
·         Once an  ectopic pregnancy  is diagnosed further  management  depends on the level of BhCG and the size   of the  ectopic  gestational  mass.




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